Have the option to go past one dozen or more museums with the opportunity to stop and visit any of them within four hours. These include, but are not limited to:
The Art Car Museum (Free)
Bayou Bend Collection and Gardens
Bible Museum
Buffalo Soldiers Museum
Byzantine Fresco Chapel Museum (Free)
The Children's Museum of Houston
Contemporary Arts Museum (Free)
Daughters of the Republic of Texas Log House (Free)
Houston African-American Museum
Houston Museum of Natural Science
Holocaust Museum Houston (Free)
Houston Fire Museum
Houston Maritime Museum
Kaplan Judaica Museum (Free)
The Jung Center of Houston (Free)
Lawndale Art Center (Free)
The Menil Collection (Free)
The Museum of Fine Arts (Free on Thursdays)
Museum of Health and Medical Science
Museum of Printing History
National Museum of Funeral History
Nature Discovery Center
The Orange Show Foundation
Railroad Museum of Gulf Coast Chapter NRHS
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Rice University Art Gallery (Free)
The Rothko Chapel (Free)
Forbidden Gardens — greater Houston
Fort Bend Museum — greater Houston
San Jacinto Museum of History — greater Houston
Spring Historical Museum — greater Houston
... and many more
Along the way, see public and folk art, and possibly visit one or more artists' studios. The folk art may be the highlight of your day and stay in Houston.
The Art Car Museum (Free) 
Houston African-American Museum 
The Menil Collection (Free)
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